Eduardo Marín-Hernández, Servicio de Dermatología Pediátrica, Hospital de Pediatría UMAE, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
Laura S. Parra-Jaramillo, Servicio de Dermatología, Centro Dermatológico Dr. Ladislao de la Pascua, Ciudad de México, México
Claudia E. Del Valle-Trigueros, Servicio de Dermatología, Hospital de Especialidades, Centro Médico Nacional Siglo XXI, Instituto Mexicano del Seguro Social (IMSS), Ciudad de México, México
Eduardo J. Marín-González, Facultad de Medicina, Universidad Nacional Autónoma de México, Ciudad de México, México
Verónica Bautista-Piña, Servicio de Anatomía Patológica, Fundación de Cáncer de Mama (FUCAM). Ciudad de México, México
Calcific perforating elastosis is a rare, acquired, and localized dermatosis that usually occurs in African American multiparous, obese women. A 67-year-old man who presented malignant hypercalcemia, who developed an ulcerated yellowish plaque covered by a chalky-like crust on the left arm. A biopsy was made that showed fragmentation, thickening, calcification and transepidermal elimination of elastic fibers. Calcific perforating elastosis associated with diffuse large B-cell mediastinal non-Hodgkin’s lymphoma was concluded. We consider this to be an exceptional case due to the association of this entity with a hematological neoplasm. A review of calcific perforating elastosis and its main differential diagnoses is performed.
Keywords: Perforating calcific elastosis. Periumbilical. Pseudoxanthoma. Non-Hodgkin lymphoma.
