Ana L. Gallmann, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Sofía C. Juárez, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Paula B. Lozano, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Julieta R. Brusa, ervicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
María N. Andrade, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Rodrigo Díaz-Alfaro, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Gabriela Sambuelli, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Mariana B. Papa, Servicio de Dermatología, Clínica Universitaria Reina Fabiola, Córdoba, Argentina
Hereditary leiomyomatosis and renal cell cancer is an autosomal dominant disorder that predisposes patients who have multiple cutaneous, uterine leiomyomas and renal cell carcinoma. Its etiology lies in a heterozygous mutation of the fumarate hydratase gene on chromosome 1q42.3-43, which can be inherited in an autosomal dominant way or occur sporadically. We present the case of a patient with multiple painful piloleiomyomas and refractory to pain therapy with oral medication, for which treatment with intralesional botulinum toxin was established, obtaining an excellent response, with considerable improvement in pain.
Keywords: Reed’s syndrome. Leiomyomatosis. Botulinum toxin.